The Marvel universe is being torn apart. You and your team of Marvel super heroes help Nick Fury launch a secret pre-emptive strike against Latveria and Lucia Von Bardas only to have to thwart her retalitaory attack on New York City. Coupled with other super hero incidents, public sentiment turns against super heroes. The Superhuman Registration Act becomes law and super heroes must register as weapons of mass destruction, and become licensed government agents with the United States government. Lines are drawn as Iron Man leads the pro-registration faction, while Captain America spearheads the stand on anti-registration. You must pick a side and fight to determine the fate of the universe and humankind. So, whose side are you on.